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SU11248 drug show promise against neuroendocrine tumors-stubborn cancers that respond poorly to chemotherapy

A unique, targeted anti-cancer drug appears to show promise against neuroendocrine tumors-stubborn cancers that have traditionally responded poorly to chemotherapy, according to research findings announced at the 2005 Annual Meeting of the American Society of Clinical Oncology (ASCO).

17 May 2005

Patients with suspicious axillary lymph nodes in their breasts should first undergo ultrasound-guided fine-needle aspiration to avoid unnecessary surgery

Currently, breast cancer patients undergo axillary lymph node dissection for accurate staging and control of the cancer. In many cases, this major procedure can be replaced by sentinel lymph node biopsy, which is a more simple and less invasive surgical procedure, but many still have to undergo axillary dissection after the sentinel lymph node biopsy.

17 May 2005

MDCT overtakes ventilation-perfusion lung scan for diagnosing pulmonary embolism

MDCT pulmonary angiography is replacing the ventilation-perfusion lung scan to diagnose suspected pulmonary embolism in hospitalized patients, say researchers from Rhode Island Hospital in Providence.

17 May 2005

Antibody combined with cancer drug shows promise against breast tumors

An antibody that targets the blood vessels nourishing tumors significantly reduced breast cancer formation and growth in mice when combined with a current cancer drug, according to researchers at UT Southwestern Medical Center.

16 May 2005

Drugs that block the enzyme Odc prevent the onset of cancers

The drug DFMO prevents cancer in laboratory models of lymphoma but fails to kill existing cancerous cells that have lost the ability to self-destruct, according to investigators at St. Jude Children's Research Hospital.

16 May 2005

Statin chemoprevention with minimal surveillance could prevent 96 percent of colon cancers

Ulcerative colitis affects about one out of every 2,000 Americans, and after living with the disease for 30 years, nearly 22 percent of those people will develop colon cancer.

16 May 2005

Scientists discover how excess body fat can lead to the onset of diabetes

One out of 12 people in the western world suffers from type 2 (adult onset) diabetes. Worldwide, 150 million people are diabetic and their numbers are expected to double in the next 20 years, a result of the growing obesity epidemic. Yet, the reasons for the strong correlation between excess body fat and diabetes have been puzzling researchers.

16 May 2005

St. John's Wort only minimally effective in relieving major depression

St. John’s Wort, the herbal medicinal long thought to relieve symptoms of depression, provides only minor benefits in patients with the most acute depression and perhaps no benefit for those with chronic depression.

16 May 2005

Bevacizumab (Avastin) combined with low-dose chemotherapy slows ovarian cancer

A targeted cancer drug given with low-dose chemotherapy shrank ovarian tumors and slowed progression of ovarian cancer in patients with recurrent disease, according to research findings presented by Agustin Garcia, M.D., principal investigator of the study and Director of Breast Cancer Research at the Women's Cancer Research Institute at the Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center.

16 May 2005

More health benefits from green tea

Green tea appears to protect against cancer by affecting a "promiscuous" protein that pharmaceutical experts are already targeting in an effort to develop a new drug to stop the disease, scientists at the University of Rochester Medical Center have found.

16 May 2005

Exaggerated blood pressure reaction to mental stress predicts cardiovascular risk

When mental stress sparks a significant rise in blood pressure, it may be a sign of other existing cardiovascular risk factors, researchers reported today at the American Society of Hypertension’s Twentieth Annual Scientific Meeting.

16 May 2005

Physical fitness and regular exercise reduces a major predictor of cardiovascular disease

Physical fitness and regular exercise reduces a major predictor of cardiovascular disease in adults with normal blood pressure or mild hypertension. Physical conditioning in the absence of medication is not, however, as advantageous to the more severe hypertensive patient, reported researchers at the American Society of Hypertension Twentieth Annual Scientific Meeting.

16 May 2005

Hour of day and time of year has significant impact on blood pressure levels

The odds of measuring an elevated blood pressure can vary by as much as 40 percent depending on the time of day and time of year, according to researchers from the Center for Health Research and Rural Advocacy at Geisinger Health System in Pennsylvania. They recommend that clinicians anticipate changes in blood pressure due to these temporal factors when diagnosing and considering treatment options for their patients.

16 May 2005

Significant non-coronary findings found during heart CT scans point to importance of trained radiologists

A significant percentage of patients undergoing targeted CT of the heart have abnormalities outside the coronary arteries, some of which could be life threatening, and as a result need the experience of trained radiologists to interpret them, say researchers from the University of Michigan Cardiovascular Center in Ann Arbor.

16 May 2005

Use of CT angiograms (CTAs) may be too high

The number of CT angiograms (CTAs) has gone up substantially, but the number of pulmonary emboli found has not, leading some researchers to question the utilization of this procedure.

16 May 2005

Accuracy of CT colonography is excellent in comparison with conventional colonoscopy for colorectal cancer screening

The diagnostic accuracy of CT colonography is excellent in comparison with conventional colonoscopy for colorectal cancer screening, an analysis of previous studies shows.

16 May 2005

Colon cancer patients who took aspirin regularly fared better after surgery

Colon cancer patients who took aspirin regularly fared better after surgery, reducing their risk of disease recurrence and death by half compared to non-users, researchers will report at the annual meeting of the American Society of Clinical Oncology.

16 May 2005

Botox injections decrease drooling in children with neurologic impairments

Ultrasound-guided Botox injections into the salivary glands decrease drooling in children with neurologic impairments such as cerebral palsy, say researchers from Toronto’s Hospital for Sick Children.

16 May 2005

Molecule found in liver cells could explain a lot about the relationship between diet, lipid levels in blood, and atherosclerosis

A team of researchers at the University of Pennsylvania School of Medicine have made a discovery that a molecule found in liver cells is important in explaining the relationship between diet, lipid levels in blood, and atherosclerosis.

15 May 2005

75,000 children end up in hospital emergency rooms due to trampoline injuries

Linakis states quite categorically that the home environment and even the school environment are not the place for trampolines. He says though it will not be a popular idea, trampolines are only appropriate in very select, heavily supervised environments, such as a gymnastics school.

15 May 2005

Medical Research News

SU11248 drug show promise against neuroendocrine tumors-stubborn cancers that respond poorly to chemotherapy

Patients with suspicious axillary lymph nodes in their breasts should first undergo ultrasound-guided fine-needle aspiration to avoid unnecessary surgery

MDCT overtakes ventilation-perfusion lung scan for diagnosing pulmonary embolism

Antibody combined with cancer drug shows promise against breast tumors

Drugs that block the enzyme Odc prevent the onset of cancers

Statin chemoprevention with minimal surveillance could prevent 96 percent of colon cancers

Scientists discover how excess body fat can lead to the onset of diabetes

St. John's Wort only minimally effective in relieving major depression

Bevacizumab (Avastin) combined with low-dose chemotherapy slows ovarian cancer

More health benefits from green tea

Exaggerated blood pressure reaction to mental stress predicts cardiovascular risk

Physical fitness and regular exercise reduces a major predictor of cardiovascular disease

Hour of day and time of year has significant impact on blood pressure levels

Significant non-coronary findings found during heart CT scans point to importance of trained radiologists

Use of CT angiograms (CTAs) may be too high

Accuracy of CT colonography is excellent in comparison with conventional colonoscopy for colorectal cancer screening

Colon cancer patients who took aspirin regularly fared better after surgery

Botox injections decrease drooling in children with neurologic impairments

Molecule found in liver cells could explain a lot about the relationship between diet, lipid levels in blood, and atherosclerosis

75,000 children end up in hospital emergency rooms due to trampoline injuries

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