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RADAR may have already saved hundreds of thousands of lives

As many as hundreds of thousands of lives may have saved by a program that identifies serious, sometimes fatal medication reactions.

4 May 2005

Penn researchers demonstrate that a metabolic enzyme works through the tumor-suppressor protein p53 to control cellular replication

Researchers at the University of Pennsylvania School of Medicine have identified in normal cells that a common metabolic enzyme, which acts as a rheostat of cellular conditions, also controls cell replication.

4 May 2005

Different consultants mean different lengths of stay in hospitals

Patients may enjoy shorter stays in hospitals depending on which consultant looks after them, according to new research published this week in Postgraduate Medical Journal.

4 May 2005

New GP contract may not improve treatment for heart failure patients

The new contract for GPs may improve identification and diagnosis of chronic heart failure, but there is a danger that it may fall short of ensuring optimal treatment for these patients, says research published this week in Postgraduate Medical Journal.

4 May 2005

Pharmacogenomics used to treat inherited kidney disorder of children

Mayo Clinic researchers have used pharmacogenomics to develop a test and treatment for an inherited kidney disorder that can cause organ failure in children and young adults.

4 May 2005

Specific variants of genes predict bleeding after heart surgery

Duke University Medical Center researchers have found that the presence of specific variants of genes that control clotting and the contractility, or "tone," of blood vessels can double the ability of physicians to predict those heart surgery patients at greatest risk of bleeding after surgery.

4 May 2005

Scalpel-free surgery could reduce risk of HIV and Hepatitis exposure for health care workers in city hospitals

While the incidence of disease from HIV and hepatitis is increasing in the United States, little is known about their prevalence in patients undergoing surgery. Now, researchers have shown that nearly 40 percent of surgeries at The Johns Hopkins Hospital occur in patients who tested positive for a bloodborne germ.

4 May 2005

Impact of acupuncture goes beyond the acknowledged placebo effect

Researchers at the University of Southampton and University College London have shown for the first time that the impact of acupuncture goes beyond the acknowledged placebo effect caused by the patient's own expectation of feeling benefit from the treatment.

4 May 2005

Researchers unravel how nature releases the torque built up in DNA at the molecular level

A Dutch led international team of researchers has unravelled how nature releases the torque built up in DNA at the molecular level. The researchers from Delft University of Technology, the Ecole Normale Supérieure in Paris and the Sloan-Kettering Institute in New York published their findings in the 31 March 2005 issue of Nature. An artistic impression of the enzyme at work is featured on the cover of this issue.

4 May 2005

Newly identified fly genes provide clue to tumour growth

Researchers from the Oxford University Department of Human Anatomy and Genetics have found a new class of genes that are critical for cell growth and may be involved in the uncontrolled growth that takes place in cancer. The discovery could provide a key to future tumour therapies.

4 May 2005

Researchers develop new method for facile identification of proteins in bacterial cells

Researchers at the Johns Hopkins Bloomberg School of Public Health have developed a new method for identifying specific proteins in whole cell extracts of microorganisms using traditional peptide mass fingerprinting (PMF).

4 May 2005

Glucose byproduct prevents brain damage after diabetic coma

A natural, non-toxic byproduct of glucose may prevent brain cell death and cognitive impairment in diabetics following an episode of severely low blood sugar, according to researchers at the San Francisco VA Medical Center (SFVAMC).

4 May 2005

Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

A new vaccine designed at The Rockefeller University boosted a type of fast-responding immune system cell called the natural killer T (NKT) cell in patients with advanced cancer. The study surprised researchers by revealing the ability of these NKT cells to spur other, slower-responding immune cells to go to work.

4 May 2005

Research suggests potential new strategies for fighting age-related vascular disease

Declining function of cells that help repair the inner lining of blood vessels, known as endothelial progenitor cells, rather than a dwindling supply of the cells, may underlie the increased risk of atherosclerosis and other vascular diseases as people grow older, according to a new study (PDF) in the May 3, 2005, issue of the Journal of the American College of Cardiology.

4 May 2005

Mutated gene causes serious heart disease in newborns

The research group of professor Manfred Kilimann at the Department of Cell and Molecular Biology has elucidated the genetic cause of a severe heart disease in newborn children. This result will be published in the June issue of the American Journal of Human Genetics this week.

3 May 2005

Diabetes researchers look at pizza to find slow and steady insulin delivery wins the race

With its doughy, carbohydrate-dense crust and high fat content, pizza can wreak havoc in people with diabetes. A Penn State Diabetes Center study suggests a slow and steady insulin-dosing pattern may best combat the glucose-raising effects of that common favorite food.

3 May 2005

Young teens are far busier sexually than we might like to think

Canadian researchers say young teens are far busier sexually than might previously have been thought and much of that activity goes undetected because it is not specifically asked about.

3 May 2005

Monitoring program has successfully identified a large number of previously unknown, serious and often-fatal drug reactions

A monitoring program developed by a Northwestern University researcher has successfully identified a large number of previously unknown, serious and often-fatal drug reactions associated with 15 commonly used drugs, including Plavix®, thalidomide and drug-coated cardiac stents.

3 May 2005

Researchers make new advances in determining the structure of all possible DNA sequences

Oregon State University researchers have made significant new advances in determining the structure of all possible DNA sequences – a discovery that in one sense takes up where Watson and Crick left off, after outlining in 1953 the double-helical structure of this biological blueprint for life.

3 May 2005

Researchers have successfully induced adult heart-muscle cells to divide and multiply

In the best documented effort to date, researchers from the Howard Hughes Medical Institute at Children's Hospital Boston and Harvard Medical School have successfully induced adult heart-muscle cells to divide and multiply.

3 May 2005

Medical Research News

RADAR may have already saved hundreds of thousands of lives

Penn researchers demonstrate that a metabolic enzyme works through the tumor-suppressor protein p53 to control cellular replication

Different consultants mean different lengths of stay in hospitals

New GP contract may not improve treatment for heart failure patients

Pharmacogenomics used to treat inherited kidney disorder of children

Specific variants of genes predict bleeding after heart surgery

Scalpel-free surgery could reduce risk of HIV and Hepatitis exposure for health care workers in city hospitals

Impact of acupuncture goes beyond the acknowledged placebo effect

Researchers unravel how nature releases the torque built up in DNA at the molecular level

Newly identified fly genes provide clue to tumour growth

Researchers develop new method for facile identification of proteins in bacterial cells

Glucose byproduct prevents brain damage after diabetic coma

Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

Research suggests potential new strategies for fighting age-related vascular disease

Mutated gene causes serious heart disease in newborns

Diabetes researchers look at pizza to find slow and steady insulin delivery wins the race

Young teens are far busier sexually than we might like to think

Monitoring program has successfully identified a large number of previously unknown, serious and often-fatal drug reactions

Researchers make new advances in determining the structure of all possible DNA sequences

Researchers have successfully induced adult heart-muscle cells to divide and multiply

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