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Protein discovery with medical implications

It was a transforming moment. Researchers could barely believe their eyes. A molecular blob of a protein reshaped itself into a molecular Pacman in order to free new viruses from the inside of a bacterial cell.

6 Jan 2005

Researchers want to see physicians reevaluate the drugs their elderly patients take to determine if they are appropriate

Just as our bodies physically slow down as we age, changes occur in the way that older bodies handle pharmaceuticals, and prescribing physicians need to be aware of those medications inappropriate for the elderly.

6 Jan 2005

Single abnormal cell can duplicate to form cancerous tumors

Researchers at the University of Pittsburgh have identified how a single aberrant cell can duplicate to form cancerous tumors, suggesting a specific protein mechanism as a target for the treatment of cancer, they report in a paper titled "Spindle Multipolarity Is Prevented by Centrosomal Clustering," published in the Jan. 7 issue of Science.

6 Jan 2005

Mutated gene may provide better idea of how cancer develops and progresses

Scientists are taking the first steps to find out how a gene that is mutated in many cancer cells functions in healthy cells.

6 Jan 2005

Processes shed light on how DNA recombination mechanisms are related

Peter W. Atkinson, a University of California, Riverside professor of entomology and member of the university’s Institute for Integrative Genome Biology, is part of a team that has linked the movement of small pieces of DNA, known as transposable elements, to a process called V(D)J recombination that produces the genetic diversity responsible for the production of antibodies.

6 Jan 2005

Gene sequencing explains why natural bioremediation 'bug' has big appetite for chlorinated pollutants

"The born-to-dechlorinate bug" is what Cornell University researchers called Dehalococcoides ethenogenes Strain 195 when they found the bacterium obligingly detoxifying the pollutant PCE, or perchloroethylene (a chlorinated solvent used for dry cleaning), in sludge from an Ithaca, N.Y., sewage treatment plant.

6 Jan 2005

In the first few days of each month, fatalities due to medication errors rise by as much as 25 percent above normal

Beware not the ides but the start of March – and April and May and every month. In the first few days of each month, fatalities due to medication errors rise by as much as 25 percent above normal, according to new research by University of California, San Diego sociologist David Phillips.

6 Jan 2005

New insights into the strategies that the brain uses to measure time

From pouring a glass of milk to typing a news article, precise timing--down to the thousandth of a second--is key to the brain's control of movement.

6 Jan 2005

Glia cells may be essential for the normal development of nerve cells responsible for hearing and balance

Traditionally viewed as supporting actors, cells known as glia may be essential for the normal development of nerve cells responsible for hearing and balance, according to new University of Utah research. The study is reported in the January 6, 2005 issue of Neuron and is co-authored by scientists at the University of Washington.

6 Jan 2005

Antibiotics protect nerves in mice by turning on genes

A family of antibiotics that includes penicillin may help prevent nerve damage and death in a wide variety of neurological diseases, including Lou Gehrig's disease, dementia, stroke, and epilepsy, Johns Hopkins researchers have found.

6 Jan 2005

Discovery of gene related to p53 called Bnip3L that can also cause cell death

Researchers have known for a decade that the p53 tumor suppressor gene is important for killing cells as they proliferate under low-oxygen conditions inside tumors.

5 Jan 2005

New hope for millions of patients suffering from liver damage (cirrhosis)

Millions of patients suffering from liver damage (cirrhosis) and failure may benefit from research by the Universities of Edinburgh and Southampton which may lead to new life-saving treatments. There is currently no cure for liver cirrhosis and a patient's only hope of survival is to receive a liver transplant.

5 Jan 2005

Protein in cardiac muscle cells may play a crucial role in heart failure prevention

Scientists at the University of North Carolina at Chapel Hill School of Medicine have shown that a protein in cardiac muscle cells may play a crucial role in heart failure prevention.

5 Jan 2005

Functional magnetic resonance imaging helps visualize the human brain as a massive, interacting, complex network

A team headed by scientists at Northwestern University, using functional magnetic resonance imaging (fMRI), has shown how to visualize the human brain as a massive, interacting, complex network governed by a few underlying dynamic principles.

5 Jan 2005

Airflow through the human nose is more complicated than that over a jumbo jet’s wing

Winter colds can give you a blocked up nose that stops you smelling chimney smoke, roasting chestnuts, warming winter puddings and the other seasonal scents.

5 Jan 2005

New genetic clues provide better understanding of epilepsy

Two specific areas in chromosome 7 and chromosome 16 have been associated with photosensitivity, an epilepsy-related trait, by a team of European scientists in the January issue of Human Molecular Genetics.

5 Jan 2005

New protein discovered holds promise for use in medicine and nanoscience

Researchers at the Hebrew University of Jerusalem have succeeded in discovering and isolating a new protein from the poplar tree with special structural and qualitative characteristics that could have consequences for development of future nanocapsules for drug delivery to cancer cells.

5 Jan 2005

Direct modulation of progesterone signaling appears to influence ovarian cancer risk

A woman's risk of ovarian cancer rises significantly if she carries either of two previously unexamined variations in the gene that codes for the progesterone receptor, according to a team of researchers led by scientists from the Keck School of Medicine of the University of Southern California.

5 Jan 2005

Depression can double the risk of death or repeat heart disease in heart attack patients

Depression can double the risk of death or repeat heart disease in heart attack patients, according to two reviews of more than 40 studies that examine the link between depression and heart disease. The reviews are published in the journal Psychosomatic Medicine.

5 Jan 2005

Calcium intake contributing factor in formation of kidney stones

Individuals with either calcium oxalate or calcium phosphate kidney stones should not take extra calcium on their own as suggested by previous research, but should check with their doctors to determine the dietary guidelines that work best for them, researchers at UT Southwestern Medical Center at Dallas have found.

4 Jan 2005

Medical Research News

Protein discovery with medical implications

Researchers want to see physicians reevaluate the drugs their elderly patients take to determine if they are appropriate

Single abnormal cell can duplicate to form cancerous tumors

Mutated gene may provide better idea of how cancer develops and progresses

Processes shed light on how DNA recombination mechanisms are related

Gene sequencing explains why natural bioremediation 'bug' has big appetite for chlorinated pollutants

In the first few days of each month, fatalities due to medication errors rise by as much as 25 percent above normal

New insights into the strategies that the brain uses to measure time

Glia cells may be essential for the normal development of nerve cells responsible for hearing and balance

Antibiotics protect nerves in mice by turning on genes

Discovery of gene related to p53 called Bnip3L that can also cause cell death

New hope for millions of patients suffering from liver damage (cirrhosis)

Protein in cardiac muscle cells may play a crucial role in heart failure prevention

Functional magnetic resonance imaging helps visualize the human brain as a massive, interacting, complex network

Airflow through the human nose is more complicated than that over a jumbo jet’s wing

New genetic clues provide better understanding of epilepsy

New protein discovered holds promise for use in medicine and nanoscience

Direct modulation of progesterone signaling appears to influence ovarian cancer risk

Depression can double the risk of death or repeat heart disease in heart attack patients

Calcium intake contributing factor in formation of kidney stones

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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