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Scientists decode inner speech from brain activity with high accuracy

Scientists have pinpointed brain activity related to inner speech-the silent monologue in people's heads-and successfully decoded it on command with up to 74% accuracy.

14 Aug 2025

New 2025 guidelines focus on early intervention and lifestyle to manage high blood pressure

Preventing and managing high blood pressure with healthy lifestyle behaviors, such as following a heart-healthy diet including reducing salt intake, staying physically active, maintaining a healthy weight and managing stress—combined with early treatment with medication to lower blood pressure if necessary—are recommended to reduce the risk of heart attack, stroke, heart failure, kidney disease, cognitive decline and dementia, according to a new clinical guideline published today in the American Heart Association's peer-reviewed journals Circulation and Hypertension, and in JACC, the flagship journal of the American College of Cardiology.

14 Aug 2025

Dual epigenetic marks found to regulate cell identity

Shedding light on what determines how cells become what they are meant to be-nerves, bone, muscles, etc.-can also help researchers understand how diseases develop when these biological programs break down.

14 Aug 2025

UC San Diego's ACTRI wins $80 million Clinical and Translational Science Award

The University of California San Diego's Altman Clinical and Translational Research Institute (ACTRI) has received a seven-year, $80 million Clinical and Translational Science Award (CTSA) from the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health.

14 Aug 2025

Mayo Clinic identifies cellular 'fountain of youth' in aging immune systems

The immune system is meant to protect the body from infection and disease. But with age, it can become less capable of doing so.

14 Aug 2025

Microbial DNA signature in the blood differentiates primary liver cancer from metastatic colorectal cancer

Determining whether a cancerous tumor originated in a given location or spread there from another tissue or organ in the body is important when assessing the likely course of a patient's disease.

14 Aug 2025

Cornell researchers create first microwave neural network on a chip

Cornell University researchers have developed a low-power microchip they call a "microwave brain," the first processor to compute on both ultrafast data signals and wireless communication signals by harnessing the physics of microwaves.

14 Aug 2025

Llama-derived nanobody VHH21 destroys the spike-trimer of SARS-CoV-2

Neutralizing antibodies that merely block receptor binding are losing ground against heavily mutated SARS-CoV-2 Omicron sub-variants.

14 Aug 2025

Rare immune mutation unlocks universal antiviral protection

For a few dozen people in the world, the downside of living with a rare immune condition comes with a surprising superpower-the ability to fight off all viruses.

14 Aug 2025

Scaffold-free cellular spheroids generate integrated osteochondral grafts

A new study in the peer-reviewed journal Tissue Engineering, Part A demonstrates the potential to produce cellular spheroids, from a clinically relevant embryonic stem cell derived mesenchymal stem cell (ES-MSC) source, to generate scaffold-free chondrogenic or osteochondrogenic graft tissues.

14 Aug 2025

Helping others regularly slows cognitive decline in older adults

In the latest evidence that meaningful social connections bolster health, a team from The University of Texas at Austin and University of Massachusetts Boston has found that regular time spent helping outside the home significantly slows cognitive decline in middle-age and older adults.

13 Aug 2025

Study identifies why stroke impairs ability to use word meanings in reading

A key discovery about the impact of stroke on a person's ability to read reveals why a deficit occurs – a finding that presents a possible opportunity for new therapeutic strategies to help people recover one of the most important life skills.

13 Aug 2025

New bioimaging device shows promise for detecting eye and heart conditions

If you've been to a routine eye exam at the optometrist's office, chances are you've had to place your chin and forehead up close to a bioimaging device.

13 Aug 2025

Microbes found to play a key role in shaping early brain development

New research from Michigan State University finds that microbes play an important role in shaping early brain development, specifically in a key brain region that controls stress, social behavior, and vital body functions.

13 Aug 2025

New technique enables efficient loading of large biomolecules into exosomes

Exosomes, naturally derived vesicles responsible for intercellular communication, are emerging as next-generation drug delivery systems capable of transporting therapeutics to specific cells.

13 Aug 2025

Pandemic left measurable changes in teen brains, hormones, and immunity

Adolescents assessed after COVID-19 lockdowns showed lower daily cortisol, higher inflammation, and reduced prefrontal cortex activity compared to matched pre-pandemic peers, suggesting widespread stress-related biological changes. These alterations mirror patterns seen after prolonged early-life stress, raising concerns about long-term health risks.

13 Aug 2025

Curcumin activates SIRT3 to protect bone structure in diabetic mice

In a new Scientific Reports study, curcumin protected bone-forming cells from high-glucose damage by activating the SIRT3/FoxO3a/NRF2 antioxidant pathway and restoring mitochondrial health. In diabetic mice, curcumin improved bone density and oxidative balance, highlighting its potential in osteoporosis prevention.

13 Aug 2025