Chemotherapy

Chemotherapy, in its most general sense, is the treatment of disease by chemicals especially by killing micro-organisms or cancerous cells. In popular usage, it refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a cytotoxic standardized treatment regimen.

What is Chemotherapy?

Chemotherapy literally refers to the treatment of certain diseases using specific chemicals that are destructive to malignant cells or to the causative agent of a disease such as a bacteria or virus. Therefore, the treatment can be broadly divided into two categories - cancer chemotherapy and antimicrobial chemotherapy.

History of Chemotherapy

Chemotherapy Treatment Schemes

What is 'Chemo Brain'?

Chemotherapy Principles

Does Scalp Cooling Prevent Hair Loss During Chemotherapy?

Chemotherapy Types

How Chemotherapy Affects Daily Living

Latest Chemotherapy News and Research

Study highlights potential of ferroptosis-based approaches to treat cancer

Therapies that target the utilization of fat by tumors and activate a type of cell death dependent on fat molecules may be a promising avenue to treat cancer, according to new research by UTHealth Houston.

14 Jan 2026

Bacterial toxin shrinks tumors, enhances immune response in colorectal cancer study

A toxin secreted by cholera bacteria can inhibit the growth of colorectal cancer without causing any measurable damage to the body. This is shown by a new study by researchers at Umeå University, Sweden.

14 Jan 2026

DLL3 on circulating tumor cells predicts tarlatamab success in lung cancer

A team led by investigators at the Mass General Brigham Cancer Institute has discovered that a particular marker on tumor cells circulating in the blood indicates whether a patient with lung cancer will experience a lasting response to a newly approved immunotherapy called tarlatamab.

14 Jan 2026

Novel immunotherapy targeting pancreatic cancer shows promising results in phase 1/2 trial

A recent publication in Nature Medicine describes a novel immunotherapy targeting pancreatic cancer that has shown promising results in a first in-human phase 1/2 trial.

13 Jan 2026

Analysis reveals why head and neck cancer clinical trials end early

Head and neck cancer trials are frequently derailed before they can deliver answers. A new analysis suggests that the most common reasons are sponsor decisions related to safety or effectiveness and poor patient recruitment.

12 Jan 2026

Alliance trial tests proactive chemotherapy dose adjustments for GI cancers

To make cancer care smoother and more effective, the Alliance for Clinical Trials in Oncology has introduced a new clinical trial for people with gastrointestinal cancers, such as cancers of the stomach, colon, and esophagus.

12 Jan 2026

Durvalumab extends survival in small cell lung cancer but raises cost concerns

A new study suggests that the immune checkpoint inhibitor, durvalumab, may offer new treatment options for patients living with small cell lung cancer (SCLC).

9 Jan 2026

Clonal hematopoiesis linked to increased heart disease risk in cancer patients receiving treatment

About 1 in 5 patients with cancer who undergo genetic testing are incidentally found to have mutations in their blood called clonal hematopoiesis of indeterminate potential (CHIP).

8 Jan 2026

Cornell-developed nanoparticles improve cancer immunotherapy effectiveness

A class of ultrasmall fluorescent core-shell silica nanoparticles developed at Cornell is showing an unexpected ability to rally the immune system against melanoma and dramatically improve the effectiveness of cancer immunotherapy, according to a new study led by Weill Cornell Medicine and Cornell Engineering researchers.

7 Jan 2026

Replenishing mitochondria significantly reduces chronic nerve pain, research shows

For millions living with nerve pain, even a light touch can feel unbearable. Scientists have long suspected that damaged nerve cells falter because their energy factories known as mitochondria don't function properly.

7 Jan 2026

Pitavastatin shows pomise in overcoming chemotherapy resistance in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is among the most aggressive types of breast cancer, lacking estrogen, progesterone, and HER2 receptors and thus relying primarily on cytotoxic chemotherapy.

7 Jan 2026

New breakthrough could modernize treatment for glioblastoma

Researchers at the UNC School of Medicine and the UNC Eshelman School of Pharmacy have made a breakthrough that could modernize treatment for glioblastoma, a fast-growing and deadly form of brain cancer.

6 Jan 2026

UH pharmacology professor wins $900,000 grant to develop a dual-function nanodrug for cancer

Accelerating advancements in cancer prevention and cures, Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, has received a $900,000 grant from the Cancer Prevention and Research Institute of Texas to develop stronger and more targeted anti-tumor therapy for pancreatic and lung cancer.

6 Jan 2026

A mathematical solution for precise control of cellular “noise”

Why does cancer sometimes recur after chemotherapy? Why do some bacteria survive antibiotic treatment? In many cases, the answer appears to lie not in genetic differences, but in biological noise - random fluctuations in molecular activity that occur even among genetically identical cells.

2 Jan 2026

Silica nanomatrix enhances immunotherapy for solid tumors

Cancer has long remained a leading cause of death worldwide and in Hong Kong, accounting for 30% of all disease-related deaths in the city in 2025. While chemotherapy remains a major treatment modality, its side effects and the risk of relapse challenges for patients.

30 Dec 2025

Inflammation and immune suppression fuel aggressive SCLC behavior and spread

Small cell lung cancer (SCLC) is one of the most aggressive forms of lung cancer, with a five-year survival rate of only five percent. Despite this poor prognosis, SCLC is initially highly responsive to chemotherapy.

30 Dec 2025

Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer

A new study published today in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center details a therapeutic vulnerability in patients with an aggressive subtype of triple-negative breast cancer.

26 Dec 2025

Artificial intelligence improves risk stratification in oropharyngeal cancer

A team led by investigators at Mass General Brigham and Dana-Farber Cancer Institute has developed and validated an artificial intelligence (AI)–based noninvasive tool that can predict the likelihood that a patient's oropharyngeal cancer-a type of head and neck cancer that develops in the throat-will spread, thereby signaling which patients should receive aggressive treatment.

23 Dec 2025

CT-based quantification of tumor fibrosis guides chemotherapy in pancreatic cancer

On October 3, 2025, a multicenter team from Shenzhen University, Xiangya Hospital of Central South University, Zhujiang Hospital of Southern Medical University, Wuxi People's Hospital Affiliated to Nanjing Medical University, among others jointly reported a novel noninvasive method for quantifying tumor fibrosis based on preoperative enhanced CT.

23 Dec 2025

Robots and click chemistry open a new frontier in antibiotic discovery

Researchers have used a cutting-edge robotic system capable of synthesizing hundreds of metal complexes to develop a possible antibiotic candidate - offering fresh hope in the global fight against drug-resistant infections.

23 Dec 2025

Chemotherapy

Overview

History of Chemotherapy

Chemotherapy Treatment Schemes

What is 'Chemo Brain'?

Feature Articles

Chemotherapy Principles

Does Scalp Cooling Prevent Hair Loss During Chemotherapy?

Chemotherapy Types

How Chemotherapy Affects Daily Living

Latest Chemotherapy News and Research

Study highlights potential of ferroptosis-based approaches to treat cancer

Bacterial toxin shrinks tumors, enhances immune response in colorectal cancer study

DLL3 on circulating tumor cells predicts tarlatamab success in lung cancer

Novel immunotherapy targeting pancreatic cancer shows promising results in phase 1/2 trial

Analysis reveals why head and neck cancer clinical trials end early

Alliance trial tests proactive chemotherapy dose adjustments for GI cancers

Durvalumab extends survival in small cell lung cancer but raises cost concerns

Clonal hematopoiesis linked to increased heart disease risk in cancer patients receiving treatment

Cornell-developed nanoparticles improve cancer immunotherapy effectiveness

Replenishing mitochondria significantly reduces chronic nerve pain, research shows

Pitavastatin shows pomise in overcoming chemotherapy resistance in triple-negative breast cancer

New breakthrough could modernize treatment for glioblastoma

UH pharmacology professor wins $900,000 grant to develop a dual-function nanodrug for cancer

A mathematical solution for precise control of cellular “noise”

Silica nanomatrix enhances immunotherapy for solid tumors

Inflammation and immune suppression fuel aggressive SCLC behavior and spread

Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer

Artificial intelligence improves risk stratification in oropharyngeal cancer

CT-based quantification of tumor fibrosis guides chemotherapy in pancreatic cancer

Robots and click chemistry open a new frontier in antibiotic discovery

Cancer Research - Second Edition eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Chemotherapy

Overview

Feature Articles

Chemotherapy Principles

Does Scalp Cooling Prevent Hair Loss During Chemotherapy?

Chemotherapy Types

How Chemotherapy Affects Daily Living

Latest Chemotherapy News and Research

Cancer Research - Second Edition eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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