Chromosome News and Research

Latest Chromosome News and Research

Researchers apply 'kitchen sink approach' to produce 16 high-quality reference genomes

The flightless kakapo of New Zealand is in trouble. The world's heaviest parrot--representing one of the most ancestral branches of the parrot family tree--is nearly extinct, with barely 200 adults plodding the underbrush of four small islands.

29 Apr 2021

Researchers try to simplify gene nomenclature across various organisms

Constantina Theofanopoulou wanted to study oxytocin. Her graduate work had focused on how the hormone influences human speech development, and now she was preparing to use those findings to investigate how songbirds learn to sing. The problem was that birds do not have oxytocin. Or so she was told.

29 Apr 2021

Marmoset study establishes standards for the new era of biodiversity genomics

The international consortium today announces a series of publications in a special collection of Nature that resulted from the first phase of the Vertebrate Genome Project (VGP) to release 16 high quality reference genomes.

29 Apr 2021

Researchers identify genetic abnormalities that drive invasiveness in head and neck cancer

A multi-institutional team of researchers has identified both the genetic abnormalities that drive pre-cancer cells into becoming an invasive type of head and neck cancer and patients who are least likely to respond to immunotherapy.

26 Apr 2021

Blood-brain barrier and its effect on the immune system play a role in schizophrenia

Like a stern bodyguard for the central nervous sytem, the blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation--at least when all is functioning normally.

21 Apr 2021

HP1a is a key epigenetic regulator that maintains chromosome integrity

The information of the human genome is encoded by approximately 3 billion DNA base pairs and packaged into 23 pairs of chromosomes.

16 Apr 2021

New genetic markers may lead to personalized treatments for lung cancer

Investigators at Wake Forest School of Medicine, part of Wake Forest Baptist Health, have identified a set of new genetic markers that could potentially lead to new personalized treatments for lung cancer.

15 Apr 2021

Inhibition of nsp14 methyltransferase as a potential antiviral target for SARS-CoV-2

Beyond vaccination, the broad-spectrum antiviral medication remdesivir has robust clinical evidence and is known as the best antiviral treatment to reduce severe COVID-19 infection in hospitalized patients. Research led by John F.X. Diffley of the Chromosome Replication Laboratory suggests a potential therapeutic target for treatment development is the viral RNA cap methyltransferases, essential for viral protein translation and immune evasion.

13 Apr 2021

Aneuploidy testing can be key in determining optimal treatment for lung cancer patients

Patients with non-small cell lung cancer (NSCLC) whose cancer cells have low levels of aneuploidy - an abnormal number of chromosomes - tend to respond better to immune checkpoint inhibitor drugs than patients with higher levels, Dana-Farber Cancer Institute researchers will report at the virtual AACR Annual Meeting 2021.

12 Apr 2021

Asymptomatic SARS-CoV-2 individuals with blood group AB at highest risk

Scientists worldwide are conducting extensive research to understand the nature of the virus, its transmission kinetics, etc. They have found a strong correlation between the ABO blood group and SARS-CoV-2 regarding its morbidity and mortality.

9 Apr 2021

Full assembly of human chromosome 8 reveals novel genes, disease risks

The full assembly of human chromosome 8 is reported this week in Nature. While on the outside this chromosome looks typical, being neither short nor long or distinctive, its DNA content and arrangement are of interest in primate and human evolution, in several immune and developmental disorders, and in chromosome sequencing structure and function generally.

8 Apr 2021

Mother's stress levels during conception could be a determinant of fetal sex

A study carried out by scientists from the University of Granada has revealed that women who experience stress both before becoming pregnant and during conception are almost twice as likely to have a girl as a boy.

6 Apr 2021

New genetic link to male infertility found

The findings published in eLife show that men with this unstable subtype of the Y chromosome have a significantly increased risk of genomic rearrangements.

1 Apr 2021

SwRI researchers part of two collaborative teams receive SAMF bioscience grants

Collaborative teams that include Southwest Research Institute staff received two of six recently awarded San Antonio Medical Foundation (SAMF) bioscience grants. SwRI, in collaboration with UT Health San Antonio and University Health System, received a nearly $200,000 grant to develop machine learning algorithms for cancer detection.

31 Mar 2021

Rare genetic variant may explain severe COVID-19 in young healthy male patients

A recent study describes the association of rare alleles in a specific gene with severe COVID-19 in young male patients.

29 Mar 2021

New approach can help identify patients at risk for esophageal cancer

A combination of esophageal brushing and extensive genetic sequencing of the sample collected can detect chromosome alterations in people with Barrett's Esophagus, identifying patients at risk for progressing to esophageal cancer, according to a new study by researchers at the Johns Hopkins Kimmel Cancer Center and Case Western Reserve University.

29 Mar 2021

New method for scDNA sequencing provides insights into breast cancer evolution

vercoming previous technical challenges with single-cell DNA (scDNA) sequencing, a group led by researchers at The University of Texas MD Anderson Cancer Center has developed a novel method for scDNA sequencing at single-molecule resolution.

24 Mar 2021

Study reveals a genetic variant linked to COVID-19 severity in young men

A study of young men with COVID-19 has revealed a genetic variant linked to disease severity.

23 Mar 2021

New technique may result in earlier and easier identification of patients with Barrett's esophagus

A new technique for sampling and testing cells from Barrett's esophagus (BE) patients could result in earlier and easier identification of patients whose disease has progressed toward cancer or whose disease is at high risk of progressing toward cancer, according to a collaborative study by investigators at Case Western Reserve University and Johns Hopkins Kimmel Cancer Center (JHKCC).

23 Mar 2021

Male fertility and androgen production may be impacted by COVID-19

An interesting new study has appeared online in the journal Hormones that discusses the effects of COVID-19 on the male and female gonads.

22 Mar 2021

Chromosome News and Research

Latest Chromosome News and Research

Researchers apply 'kitchen sink approach' to produce 16 high-quality reference genomes

Researchers try to simplify gene nomenclature across various organisms

Marmoset study establishes standards for the new era of biodiversity genomics

Researchers identify genetic abnormalities that drive invasiveness in head and neck cancer

Blood-brain barrier and its effect on the immune system play a role in schizophrenia

HP1a is a key epigenetic regulator that maintains chromosome integrity

New genetic markers may lead to personalized treatments for lung cancer

Inhibition of nsp14 methyltransferase as a potential antiviral target for SARS-CoV-2

Aneuploidy testing can be key in determining optimal treatment for lung cancer patients

Asymptomatic SARS-CoV-2 individuals with blood group AB at highest risk

Full assembly of human chromosome 8 reveals novel genes, disease risks

Mother's stress levels during conception could be a determinant of fetal sex

New genetic link to male infertility found

SwRI researchers part of two collaborative teams receive SAMF bioscience grants

Rare genetic variant may explain severe COVID-19 in young healthy male patients

New approach can help identify patients at risk for esophageal cancer

New method for scDNA sequencing provides insights into breast cancer evolution

Study reveals a genetic variant linked to COVID-19 severity in young men

New technique may result in earlier and easier identification of patients with Barrett's esophagus

Male fertility and androgen production may be impacted by COVID-19

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Chromosome News and Research

Latest Chromosome News and Research

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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