Fatty Liver

Fatty liver, also known as fatty liver disease (FLD), is a reversible condition where large vacuoles of triglyceride fat accumulate in liver cells via the process of steatosis (i.e. abnormal retention of lipids within a cell).

What is Fatty Liver?

Fatty liver is a very common disorder and up to 20 percent of adults and approximately 5 percent of children are affected.

Fatty Liver Pathology

Fatty Liver Diagnosis

Acute Fatty Liver of Pregnancy Treatment

Gut bacteria compound during pregnancy protects offspring from fatty liver disease

Children born to mothers who consume a high-fat, high-sugar diet during pregnancy and breastfeeding face a higher risk of developing fatty liver disease later in life.

14 Jan 2026

Blocking liver enzyme Caspase-2 may increase long-term cancer risk

Scientists have discovered that blocking a key cellular enzyme thought to protect against fatty liver disease may instead increase the risk of chronic liver damage and cancer as we age.

13 Jan 2026

Metabolic BMI reveals hidden health risks in normal weight individuals

People of normal weight may also be at risk of diabetes and similar diseases. A study from the University of Gothenburg reveals that those with an unexpectedly high so-called metabolic BMI have up to a five times higher risk level.

12 Jan 2026

Forever chemicals linked to higher liver disease risk in adolescents

A new study co-led by the Southern California Superfund Research and Training Program for PFAS Assessment, Remediation and Prevention (ShARP) Center and the University of Hawai'i has linked certain common "forever chemicals" to a higher risk of liver disease in adolescents.

6 Jan 2026

Prediabetes prevalence doubles over two decades in Finnish children with obesity

The prevalence of prediabetes has increased significantly in recent years among Finnish children living with overweight or obesity, a recent study by Tampere University and the University of Eastern Finland shows.

30 Dec 2025

Discovery of fat-regulating enzyme points to a new obesity therapy

Obesity is a global epidemic and a major cause of morbidity and mortality because it increases the risk for comorbidities, including heart disease and fatty liver disease (MASLD).

23 Dec 2025

New CPRIT awards expand cancer prevention and treatment research in South Texas

UT Health San Antonio, the academic health center of The University of Texas at San Antonio (UT San Antonio), received nearly $3 million in new academic and prevention awards as part of the latest funding round announced by the Cancer Prevention Research Institute of Texas (CPRIT).

19 Dec 2025

Scientists unravel how citrin deficiency can trigger fat buildup in the liver even in lean individuals

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. and a leading research center for diabetes and other life-threatening illnesses, have unraveled how citrin deficiency (CD), a rare genetic disorder that prevents the liver from converting food into energy efficiently, can trigger fat buildup in the liver - even in lean individuals.

18 Dec 2025

High fructose intake increases fatty liver risk

Excessive fructose intake from soft drinks is linked to liver damage and NAFLD. Lifestyle modifications are essential for effective prevention and treatment.

16 Dec 2025

Uncovering the hidden metabolic effects of soybean oil

Soybean oil, the most widely consumed cooking oil in the United States and a staple of processed foods, contributes to obesity, at least in mice, through a mechanism scientists are now beginning to understand.

27 Nov 2025

Combined healthy eating and exercise linked to greater reductions in visceral fat

Improving diet and increasing physical activity levels together may be more effective at preventing weight gain – particularly harmful fat inside the abdomen – than just changing one of these behaviours, new research from the University of Cambridge suggests.

21 Nov 2025

Reduced ketone body metabolism may be key to impaired energy production in type 2 diabetes

The liver plays a central role in storing and supplying energy to the body. In type 2 diabetes and metabolic dysfunction-associated steatotic liver disease (MASLD, commonly referred to as fatty liver disease), mitochondria-the cell's power plants-cannot switch efficiently between fuel sources.

21 Nov 2025

BMI is failing to detect dangerous obesity as people age

A landmark study finds waist-to-height ratio more effective than BMI in identifying obesity risk, as central fat levels rise across the UK population.

19 Nov 2025

Understanding leptin's dual function in MAFLD pathogenesis

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic syndrome.

14 Nov 2025

Mursla Bio collaborates with a leading global pharma company to advance biomarker-guided precision medicine in MASH

Mursla Bio, a leader in Extracellular Vesicle (EV) science on a mission to advance precision diagnostics and significantly improve chronic disease outcomes for at-risk patients, today announced a collaboration with a leading global pharmaceutical company recognized for its expertise in precision medicine and biomarker-guided drug development.

From Mursla Bio 13 Nov 2025

Exosomes identified as key mediators in obstructive sleep apnea and its comorbidities

Obstructive sleep apnea (OSA), a global public health issue marked by repeated upper airway collapse during sleep, is tied to diverse diseases-from cardiovascular conditions to cancer.

12 Nov 2025

Potential breakthrough in treating acute kidney injury with ceramide-targeting drugs

Serious damage to short-term kidney function-known as acute kidney injury, or AKI-can be fatal and also increase the risk of irreversible chronic kidney disease. It can be triggered by stressors ranging from sepsis to heart surgery, and it affects more than half of ICU patients.

12 Nov 2025

Novel triple receptor agonist shows potent efficacy in lowering high triglycerides

In a small, short duration trial (12 weeks), a new medication called DR10624 reduced triglyceride levels in most patients with severe hypertriglyceridemia by more than 60%, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

Weill Cornell Medicine investigators have identified an early step in a cellular process that leads to inflammation in fat cells and may result in type 2 diabetes in people with obesity.

10 Nov 2025

How artificial light interferes with liver health

People who work against their internal clock over a long period of time increase the risk of fatty liver. The correlations are complex, but one research team in Bochum is trying to get to the bottom of the issue.

4 Nov 2025

Fatty Liver

Overview

Fatty Liver Pathology

Fatty Liver Diagnosis

Acute Fatty Liver of Pregnancy Treatment

Latest Fatty Liver News and Research

Gut bacteria compound during pregnancy protects offspring from fatty liver disease

Blocking liver enzyme Caspase-2 may increase long-term cancer risk

Metabolic BMI reveals hidden health risks in normal weight individuals

Forever chemicals linked to higher liver disease risk in adolescents

Prediabetes prevalence doubles over two decades in Finnish children with obesity

Discovery of fat-regulating enzyme points to a new obesity therapy

New CPRIT awards expand cancer prevention and treatment research in South Texas

Scientists unravel how citrin deficiency can trigger fat buildup in the liver even in lean individuals

High fructose intake increases fatty liver risk

Uncovering the hidden metabolic effects of soybean oil

Combined healthy eating and exercise linked to greater reductions in visceral fat

Reduced ketone body metabolism may be key to impaired energy production in type 2 diabetes

BMI is failing to detect dangerous obesity as people age

Understanding leptin's dual function in MAFLD pathogenesis

Mursla Bio collaborates with a leading global pharma company to advance biomarker-guided precision medicine in MASH

Exosomes identified as key mediators in obstructive sleep apnea and its comorbidities

Potential breakthrough in treating acute kidney injury with ceramide-targeting drugs

Novel triple receptor agonist shows potent efficacy in lowering high triglycerides

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

How artificial light interferes with liver health

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Fatty Liver

Overview

Latest Fatty Liver News and Research

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Newsletters you may be interested in