Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

SARS-CoV-2 Mpro inhibitor, nirmatrelvir, found to reduce COVID-19 progression and death

In a new study, researchers evaluated the efficacy and safety of nirmatrelvir in mild to moderate COVID-19 patients who were at high risk of severe COVID-19 disease.

18 Feb 2022

The ability of therapeutic monoclonal antibodies to neutralize SARS-CoV-2 Omicron BA.2 variant

Researchers evaluated the neutralizing capacity of the clinically approved mAbs against the SARS-CoV-2 Omicron BA.2 variant.

18 Feb 2022

Demonstrating effectiveness of BNT162b2 vaccine in preventing reinfections after COVID-19 recovery

Researchers conducted a retrospective cohort study to assess the rate of SARS-CoV-2 reinfection in patients who had recovered from COVID-19.

18 Feb 2022

Meta-analysis of population-based seroprevalence studies to estimate SARS-CoV-2 seroprevalence in Africa

Researchers conducted a descriptive meta-analysis to estimate the seroprevalence of SARS-CoV-2 infections in Africa.

18 Feb 2022

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Researchers characterized the responses of the PBMCs at the individual cell and cell type levels against SARS-CoV-2 and SARS-CoV ex vivo.

18 Feb 2022

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Researchers evaluated the efficacy of an mRNA vaccine booster dose against severe acute respiratory syndrome coronavirus-2 during the Omicron surge.

18 Feb 2022

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

Researchers investigated the connecting link between viral genetic variability and clinical heterogeneity of COVID-19 by analyzing the effect of several missense mutations on the ACE2 receptor coding sequence.

18 Feb 2022

Changes in the brain cortex of COVID-19 patients associated with inflammatory biomarkers

Recently, a team of researchers examined the neurotoxic damage to the brain’s cortical region in patients hospitalized due to COVID-19.

18 Feb 2022

Immunogenicity, efficacy, and safety of BNT162b2 or mRNA1273 fourth dose

A recent study explored the safety, immunogenicity, and VE of the SARS-CoV-2 mRNA BNT162b2 and mRNA1273 vaccines against its Omicron VOC in HCWs in Israel.

18 Feb 2022

mRNA vaccine-induced antibodies shown to be more effective in neutralizing SARS-CoV-2 and its variants than natural immunity

Researchers designed an electrochemiluminescence-based serology test with remarkable sensitivity to precisely quantify the amounts of anti-RBD antibodies in individuals infected with SARS-CoV-2.

18 Feb 2022

Study shows mink can be infected by Omicron and efficiently transmit the virus to other mink

Researchers have been examining the pathology and spread of the Omicron variant in mink.

18 Feb 2022

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Researchers developed a ‘bait and capture’ system which was further followed by a multiplexed and targeted proteomic liquid chromatography-tandem mass spectrometry analyses for the comparison of immune correlates in response to vaccination, natural infection, as well as protection against SARS-CoV-2 variants.

18 Feb 2022

Study finds antigenic profile of Omicron RBD is distinct from the prior SARS-CoV-2 variants of concern

A new study aimed to clarify whether extensive RBD mutations could affect the magnitude and immunodominance hierarchy of the host antibody response.

18 Feb 2022

COVID test-to-return may help shorten time away from school

In a recent study posted to the medRxiv* preprint server, a test-to-return approach for students in isolation is explored for its utility in sorting out students who can safely return to school without jeopardizing others, from those with a high viral load.

17 Feb 2022

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

SARS-CoV-2 Mpro inhibitor, nirmatrelvir, found to reduce COVID-19 progression and death

The ability of therapeutic monoclonal antibodies to neutralize SARS-CoV-2 Omicron BA.2 variant

Demonstrating effectiveness of BNT162b2 vaccine in preventing reinfections after COVID-19 recovery

Meta-analysis of population-based seroprevalence studies to estimate SARS-CoV-2 seroprevalence in Africa

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

Changes in the brain cortex of COVID-19 patients associated with inflammatory biomarkers

Immunogenicity, efficacy, and safety of BNT162b2 or mRNA1273 fourth dose

mRNA vaccine-induced antibodies shown to be more effective in neutralizing SARS-CoV-2 and its variants than natural immunity

Study shows mink can be infected by Omicron and efficiently transmit the virus to other mink

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Study finds antigenic profile of Omicron RBD is distinct from the prior SARS-CoV-2 variants of concern

COVID test-to-return may help shorten time away from school

How accurate are rapid antigen COVID tests?

Trial of early antiviral therapy for COVID-19 shows no significant benefit

Faster transmission of SARS-CoV-2 Delta variant in households compared to Alpha

Study explores the high viral loads of SARS-CoV-2 Delta and Alpha variants

Study explores humoral and cellular immunity conferred by second and third COVID-19 BNT162b2 vaccination in elderly

COVID-19 vaccine-induced immunity in heart and kidney solid organ transplant recipients

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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