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Genetic variants influencing vitamin D synthesis, metabolism, and transport

A Canadian review synthesizes genetic factors that influence vitamin D synthesis, metabolism, and transport, highlighting how polymorphisms affect circulating levels. It also explores how gene-environment interactions shape individual responses to supplementation and sunlight.

20 Aug 2025

Cancer cells break down nerve covers causing immune exhaustion and therapy resistance

Cancer cells can break down the protective covers around nerves, causing nerve injury that triggers chronic inflammation leading to immune exhaustion and eventual resistance to immunotherapy, according to new research from The University of Texas MD Anderson Cancer Center.

20 Aug 2025

New genetic study reveals why people age differently

It's a fact of life: Some people age better than others. Some ease into their 90s with mind and body intact, while others battle diabetes, Alzheimer's or mobility issues decades earlier.

20 Aug 2025

Ciliary Hedgehog signaling controls the fate of fat precursor cells

Too much fat can be unhealthy: how fat cells, so-called adipocytes, develop, is crucial for the function of the fat tissue.

20 Aug 2025

ChronODE method offers precision in timing gene therapy treatments

A Yale research team has created a new computer tool that can pinpoint when exactly genes turn on and off over time during brain development - a finding that may one day help doctors identify the optimal window to deploy gene therapy treatments.

20 Aug 2025

INTEGRA's PIPETBOY GENIUS provides superior ergonomics and liquid control for cell culture

Scientists at the Max Planck Institute of Biochemistry in Munich, Germany, use 4 PIPETBOY GENIUS serological pipet controllers from INTEGRA Biosciences to streamline their cell culture workflows.

From INTEGRA Biosciences 20 Aug 2025

PathoPlex technology maps protein patterns across human organs

Each organ in the human body contains different types of cells arranged in specific ways.

19 Aug 2025

Researchers capture first 3D real-time images of human embryo implantation

Researchers at the Institute for Bioengineering of Catalonia (IBEC) in collaboration with the Dexeus University Hospital have captured unparalleled images of a human embryo implanting.

18 Aug 2025

Fucosylation emerges as a key player in digestive inflammatory diseases and cancers

Fucosylation, a crucial post-translational modification, has emerged as a significant factor influencing digestive inflammatory diseases and cancers.

18 Aug 2025

FastUKB transforms UK Biobank research with seamless data extraction and analysis

FastUKB is an innovative tool specifically developed to streamline and enhance research workflows utilizing the UK Biobank, effectively addressing key limitations of existing platforms such as the UK Biobank Research Analysis Platform (RAP).

18 Aug 2025

RNA quality control protein PELOTA found to slow aging and extend lifespan

As aging progresses, the quality of DNA and proteins inside cells declines, known to be the cause of various degenerative diseases.

18 Aug 2025

Endoplasmic reticulum controls cell movement to repair tissue gaps

The body's cells change their shape to close gaps such as wounds – with part of the cell flexing depending on the curve of the gap and the organization of cell-internal structures, a new study reveals.

18 Aug 2025

Exploring the complex origins of endothelial cells in tumor angiogenesis

This newly published review article offers a comprehensive examination of the complexities of tumor angiogenesis and the origins of endothelial cells (ECs) within tumors.

18 Aug 2025

Study shows promising anti-diabetic potential of coffee's functional components

Three of the compounds demonstrated significant inhibitory effects on α-glucosidase, a key enzyme in carbohydrate digestion. The findings could pave the way for new functional food ingredients targeting type 2 diabetes.

18 Aug 2025

New AAV gene therapy reverses age-related macular degeneration

Neovascular age-related macular degeneration (nAMD) is a progressive eye disease characterized by choroidal neovascularization and subretinal hemorrhage and exudation, leading to vision impairment. Current first-line treatment for nAMD are anti-VEGF agents, which has shown promising therapeutics outcomes.

18 Aug 2025

2025 Chikungunya outbreak: A global health challenge

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus causing fever, severe joint pain, rash, and muscle aches, mainly transmitted by Aedes mosquitoes. As of 2025,

From Sino Biological Inc. 18 Aug 2025

New generation of CRISPR shows safer path to treating genetic diseases

A new generation of CRISPR technology developed at UNSW Sydney offers a safer path to treating genetic diseases like Sickle Cell, while also proving beyond doubt that chemical tags on DNA - often thought to be little more than genetic cobwebs - actively silence genes.

17 Aug 2025

Dementia-like protein clumping found in early pancreatic cancer cells

Cancer Research UK-funded scientists have uncovered dementia-like behaviour in pancreas cells at risk of turning into cancer. The findings provide clues that could help in the treatment and prevention of pancreatic cancer, a difficult-to-treat disease linked to 6,900 deaths in the UK every year.

17 Aug 2025

Reengineered enzyme enables precise detection of cell surface glycans

Sugars known as glycans form dense envelopes around cells. But they're often ignored in biological investigations because, unlike DNA, proteins and other cellular components, tools to study them are lacking.

14 Aug 2025

Engineered telomerase RNA offers temporary boost to telomere length in human stem cells

Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres - regions of repetitive DNA sequences and a protein structure - protect the tips of chromosomes from damage.

14 Aug 2025