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GLP-1 drugs beat metformin for weight control in teens with type 2 diabetes

In youth newly diagnosed with type 2 diabetes, GLP-1–based therapies, including semaglutide and tirzepatide, achieved similar blood sugar control but significantly greater reductions in body mass index than metformin. These findings highlight the potential of high-potency GLP-1 agents as effective monotherapy options in managing obesity and glycemic control in adolescents.

10 Nov 2025

Listening to slow-tempo music may boost sleep quality for people over 50

Music therapy significantly improves sleep quality in adults aged 50 and above, showing a moderate-to-large effect compared with control conditions. However, high heterogeneity and methodological weaknesses mean the evidence remains of very low certainty and requires confirmation in larger, standardized trials.

10 Nov 2025

Health care costs jump to the fore as candidates jockey to be California governor

California's gubernatorial election is a year away, and the field of primary candidates is still taking shape. But one persistent issue has already emerged as a leading concern: the cost of health care.

10 Nov 2025

Blood protein pattern linked to increased risk of hereditary atherosclerosis

A specific pattern of proteins in the blood may reflect an increased risk of hereditary atherosclerosis. This is shown in a new study from Karolinska Institutet, examining close relatives of people who had suffered a heart attack at a young age.

10 Nov 2025

Diabetes drugs semaglutide and tirzepatide show real-world heart benefits

In a large real-world analysis across three U.S. healthcare databases, semaglutide and tirzepatide showed cardiovascular benefits consistent with randomized trials. Semaglutide lowered heart attack and stroke risk versus sitagliptin, while tirzepatide performed comparably to dulaglutide and semaglutide over one year.

10 Nov 2025

Study advances the possibility of age-based pancreatic cancer treatment

While some risk factors for cancer can be mitigated through lifestyle choices such as diet or exercise, aging is not one of them. In the case of pancreatic cancer, it also can limit treatment options if a patient is too frail to be safely treated with surgery or other alternatives.

10 Nov 2025

Babies show stronger brain response to their mothers’ voices

In a new JNeurosci paper, Sarah Jessen and colleagues, from the University of Lübeck, explored how infants track their mothers' voices compared to unfamiliar voices.

10 Nov 2025

One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial

In a 15-patient, Phase 1 one, first-in-human trial, a one-time, CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and triglycerides in people with difficult-to-treat lipid disorders, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Daily oral medication matches injectable therapies in reducing bad cholesterol

Among people with a previous heart attack or stroke, or who are at high risk for one, a daily oral medication may offer an effective alternative to injections of PCSK9 inhibitors to lower low-density lipoprotein (LDL or "bad" cholesterol), according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Standard care found to be the better choice for older people with irregular heart rhythms

For older people with irregular heart rhythms who are at high risk of stroke and bleeding, standard care (including the use of blood thinners when indicated) was found to be the better choice compared to a promising, catheter-based procedure, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

PCSK9 inhibitor combined with a statin may help reduce LDL cholesterol after heart transplant

The cholesterol medication alirocumab, a PCSK9 inhibitor, combined with a statin appeared to reduce LDL cholesterol levels by more than 50% among patients after a heart transplant, according to a late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

One cup of coffee a day could keep atrial fibrillation from coming back

A multicenter randomized clinical trial found that moderate caffeinated coffee intake after cardioversion significantly lowered the recurrence of atrial fibrillation or flutter compared with abstinence. The findings challenge long-standing advice to avoid coffee in cardiac arrhythmia patients and support its safety at typical consumption levels.

10 Nov 2025

Understanding communication complexity among infants with neurogenetic syndromes

Nancy Brady has been gratified to see the tool she and colleagues pioneered over a decade ago to measure the growth of infants' pre-speech communication skills translated into several languages and referenced in more than 100 research papers, including a åçnew one published in the Journal of Speech, Language and Hearing Research.

10 Nov 2025

Study reveals double trouble for peripheral arterial disease patients with AFib

New research from Intermountain Health in Salt Lake City finds that patients diagnosed with peripheral arterial disease (PAD) who also have atrial fibrillation (AFib) face a significantly higher risk of major adverse cardiovascular events (MACE).

10 Nov 2025

Type 2 diabetes patients face an elevated risk of hearing loss

As the United States observes American Diabetes Month this November, a comprehensive study published in Otolaryngology–Head and Neck Surgery, the peer-reviewed journal of the American Academy of Otolaryngology–Head and Neck Surgery Foundation, reveals that individuals with type 2 diabetes face a significantly elevated risk of hearing loss-a complication that often goes unrecognized and unscreened.

10 Nov 2025

Study finds reduced cortical choline levels in people with anxiety disorders

People with anxiety disorders have lower levels of choline in their brains, according to research from UC Davis Health.

10 Nov 2025

Study provides insights into the obesity–breast cancer link

Obesity and cancer are two major health challenges of our time, yet the link between them remains only partially understood.

10 Nov 2025

Researchers develop multiethnic model for identifying individuals with skin cancer

Researchers at the University of California San Diego School of Medicine have developed a new approach for identifying individuals with skin cancer that combines genetic ancestry, lifestyle and social determinants of health using a machine learning model.

10 Nov 2025

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

Weill Cornell Medicine investigators have identified an early step in a cellular process that leads to inflammation in fat cells and may result in type 2 diabetes in people with obesity.

10 Nov 2025

Long-term poverty and rising unsecured debt may increase risk of premature mortality

Adults who experience poverty-level family income-whether sustained or intermittent-over two decades spanning young to mid-adulthood face a significantly higher risk of dying prematurely than those who are never in poverty, according to new research led by Columbia University Mailman School of Public Health.

10 Nov 2025

Medical News

GLP-1 drugs beat metformin for weight control in teens with type 2 diabetes

Listening to slow-tempo music may boost sleep quality for people over 50

Health care costs jump to the fore as candidates jockey to be California governor

Blood protein pattern linked to increased risk of hereditary atherosclerosis

Diabetes drugs semaglutide and tirzepatide show real-world heart benefits

Study advances the possibility of age-based pancreatic cancer treatment

Babies show stronger brain response to their mothers’ voices

One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial

Daily oral medication matches injectable therapies in reducing bad cholesterol

Standard care found to be the better choice for older people with irregular heart rhythms

PCSK9 inhibitor combined with a statin may help reduce LDL cholesterol after heart transplant

One cup of coffee a day could keep atrial fibrillation from coming back

Understanding communication complexity among infants with neurogenetic syndromes

Study reveals double trouble for peripheral arterial disease patients with AFib

Type 2 diabetes patients face an elevated risk of hearing loss

Study finds reduced cortical choline levels in people with anxiety disorders

Study provides insights into the obesity–breast cancer link

Researchers develop multiethnic model for identifying individuals with skin cancer

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

Long-term poverty and rising unsecured debt may increase risk of premature mortality

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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