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Children with multiple long-term conditions face nearly threefold higher COVID-19 mortality

Individuals with multiple long-term conditions are two and a half times more likely to die following COVID-19 infection than others.

18 Oct 2025

Belzutifan demonstrates strong clinical activity in two rare neuroendocrine tumors

A multicenter Phase II clinical trial led by researchers at The University of Texas MD Anderson Cancer Center demonstrated significant tumor shrinkage and disease control in patients with advanced pheochromocytoma and paraganglioma (PPGL), two rare and potentially life-threatening neuroendocrine tumors.

18 Oct 2025

Oral combination regimen improves survival in ER-positive HER-2-negative breast cancer

Patients with estrogen-receptor-positive HER-2-negative advanced breast cancer showed significantly improved progression-free survival when treated with an oral combination regimen that includes giredestrant, a novel, next-generation selective estrogen receptor degrader and full antagonist, compared to a standard combination approach.

18 Oct 2025

Targeted therapy combination shows superior outcomes in advanced kidney cancer

Results from a trial led by researchers from The University of Texas MD Anderson Cancer Center showed that a targeted therapy combination improved outcomes for patients with metastatic clear-cell renal carcinoma (ccRCC) – a type of kidney cancer – whose disease progressed following immunotherapy.

18 Oct 2025

New antibody drug conjugates can transform early HER2-positive breast cancer treatment

In a landmark moment at the ESMO Congress 2025, pivotal studies have unveiled compelling evidence that a new class of anti-cancer agents-antibody-drug conjugates (ADCs)-can dramatically improve outcomes for patients with early-stage HER2-positive breast cancer.

18 Oct 2025

Nanoparticles offer new hope for treating alcohol-related liver disease

Across the world, more than 1.5 billion people suffer from chronic liver disease. The U.S. Centers for Disease Control and Prevention reports that it kills more than 52,000 people a year in the United States alone - the ninth most common cause of death in the nation.

17 Oct 2025

Nanoplastics with environmental coatings can sneak past the skin's defenses

Plastic is ubiquitous in the modern world, and it's notorious for taking a long time to completely break down in the environment - if it ever does.

17 Oct 2025

Study reveals how a microglial mutation increases risk for Alzheimer's disease

Dominika Pilat, PhD, and Ana Griciuc, PhD, of the Department of Neurology at Massachusetts General Hospital are the lead and senior authors of a paper published in Neuron, "The Gain-of-Function TREM2-T96K Mutation Increases Risk for Alzheimer's Disease by Impairing Microglial Function."

17 Oct 2025

Study highlights the emotional and social challenges of stroke recovery

Nirupama Yechoor, MD, MSC, of the Department of Neurology at Massachusetts General Hospital, is the senior author of a paper published in JAMA Network Open, "Coherence of Stroke Survivors' Lived Experiences and the Stroke Specific Quality of Life Scale."

17 Oct 2025

European societies launch EndoCompass to guide the future of endocrine research

The European Society for Endocrinology (ESE) and the European Society for Paediatric Endocrinology (ESPE) have released today, 17 October 2025, the EndoCompass Research Roadmap: Directions for the Future of Endocrine Science.

17 Oct 2025

CRATERs identified as key sites for T cell-mediated tumor destruction

Like the surface of the moon, new research published today in Cell finds the existence of craters on the surface of melanoma cells that serve as immune hubs, becoming major sites for tumor killing. These craters could serve as good markers for immunotherapy success.

17 Oct 2025

Stroke experts call for ethical guardrails as AI expands in clinical research

As artificial intelligence (AI) use continues to grow in nearly every industry, it is important to establish guardrails to make sure the technology is used ethically and responsibly. This is especially true in the field of medicine, where errors can be a matter of life and death and patient information must be protected.

17 Oct 2025

Supportive signals during pregnancy ease return-to-work transition for women

Returning to work after maternity leave can leave new mothers wrestling with guilt – feeling they can't fully win at work or home.

17 Oct 2025

Researchers achieve proof of concept for generating eggs from somatic cells

Researchers at Oregon Health & Science University have accomplished a unique proof of concept to treat infertility by turning skin cells into eggs capable of producing early human embryos.

17 Oct 2025

Review reveals how paternal lifestyle shapes sperm epigenetics and offspring health

A new review in Clinical Epigenetics synthesises growing evidence that paternal lifestyle and environmental exposures such as diet, obesity, smoking, endocrine-disrupting chemicals, and stress alter sperm epigenetic marks (DNA methylation, histone retention, and small non-coding RNAs).

17 Oct 2025

New 3D human brain tissue platform integrates all major brain cell types into a single culture

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture.

17 Oct 2025

How task engagement reshapes the brain’s auditory processing

When we are engaged in a task, our brain's auditory system changes how it works. One of the main auditory centers of the brain, auditory cortex, is filled with neural activity that is not sound driven – rather, this activity times the task, each neuron ticking at a different moment during task performance.

17 Oct 2025

Medical News

Children with multiple long-term conditions face nearly threefold higher COVID-19 mortality

Belzutifan demonstrates strong clinical activity in two rare neuroendocrine tumors

Oral combination regimen improves survival in ER-positive HER-2-negative breast cancer

Targeted therapy combination shows superior outcomes in advanced kidney cancer

New antibody drug conjugates can transform early HER2-positive breast cancer treatment

Nanoparticles offer new hope for treating alcohol-related liver disease

Nanoplastics with environmental coatings can sneak past the skin's defenses

Study reveals how a microglial mutation increases risk for Alzheimer's disease

Study highlights the emotional and social challenges of stroke recovery

European societies launch EndoCompass to guide the future of endocrine research

CRATERs identified as key sites for T cell-mediated tumor destruction

Stroke experts call for ethical guardrails as AI expands in clinical research

Supportive signals during pregnancy ease return-to-work transition for women

Researchers achieve proof of concept for generating eggs from somatic cells

Review reveals how paternal lifestyle shapes sperm epigenetics and offspring health

New 3D human brain tissue platform integrates all major brain cell types into a single culture

How task engagement reshapes the brain’s auditory processing

Research reveals how immune cells orchestrate the release of toxic granules

Global leaders unite to invest in health for economic growth

Scientists discover why a powerful leukemia drug fails in most patients

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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