Blood-Based Biomarkers pTau217 and pTau181: Transforming Alzheimer’s Disease Diagnosis and Research

	Neurology & Neuroscience
	The latest neurology news from News Medical

The rapid evolution of plasma biomarkers like pTau217 and pTau181 has fundamentally shifted the diagnostic and research landscape for Alzheimer’s disease. BioIVT highlights core findings from peer-reviewed studies and regulatory documents along with challenges, scientific rationale, assay platforms, diagnostic workflows, clinical utility of these biomarkers, and more.

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Neurons on Fire: The MedTech Revolution You Can’t Afford to Miss

An evidence-aware briefing on seven forces reshaping neurology MedTech, with case examples, regulatory / reimbursement takeaways, and practical next steps for product and program leaders.

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New breakthrough could modernize treatment for glioblastoma

Researchers at the UNC School of Medicine and the UNC Eshelman School of Pharmacy have made a breakthrough that could modernize treatment for glioblastoma, a fast-growing and deadly form of brain cancer.

	Unveiling IDH-mutant glioma's roots: A new path for early diagnosis IDH-mutant glioma, caused by abnormalities in a specific gene (IDH), is the most common malignant brain tumor among young adults under the age of 50.

	APOE gene: A major driver in Alzheimer's disease Potentially more than 90% of Alzheimer's disease cases would not occur without the contribution of a single gene (APOE), according to a new analysis led by UCL researchers.

	Weaker and fragmented circadian rhythms linked to higher dementia risk Circadian rhythms that are weaker and more fragmented are linked to an increased risk of dementia, according to a new study published on December 29, 2025, in Neurology®, the medical journal of the American Academy of Neurology.

	Why individual differences hold the key to unlocking psychiatric mysteries In a revealing Genomic Press Interview published today in Genomic Psychiatry, Dr. Noritaka Ichinohe challenges a foundational assumption that has quietly constrained psychiatric research for decades: the belief that meaningful explanation requires averaging away individual differences.

	Struggling to make ends meet may slow brain development in infants Researchers identify specific psychosocial factors that strongly correlate with altered brain development within the first year of life.

	Microglia help protect the spinal cord from age-related damage Researchers at Karolinska Institutet have discovered that the nervous system's own immune cells help protect the spinal cord from age-related damage.

	Interferon Response in Female Brains Linked to Alzheimer's Progression More than seven million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's Association. The O'Banion Lab at the Del Monte Institute for Neuroscience at the University of Rochester has long been studying this disease and is looking more closely at the differences between male and female brains.

	New Method Turns Glial Cells Directly Into Parvalbumin Neurons Parvalbumin cells play a central role in keeping brain activity in equilibrium. They control nervcell signaling, reduce overactivity and make sure that the brain is working to a rhythm.

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