Newly identified rare genetic variant reduces the risk of leukemia
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 First human 'lung-on-chip' model developed using stem cells from a single donorFirst human 'lung-on-chip' model developed using stem cells from a single donor
 
Researchers at the Francis Crick Institute and AlveoliX have developed the first human 'lung-on-chip' model using stem cells taken from only one person.
 
 
 Newly identified rare genetic variant reduces the risk of leukemiaNewly identified rare genetic variant reduces the risk of leukemia
 
A newly identified and rare genetic variant slows the growth of mutated blood stem cells, researchers report, and it reduces the risk of leukemia.
 
   Epigenetic plasticity in germinal center B cells may help explain lymphoma originsEpigenetic plasticity in germinal center B cells may help explain lymphoma origins
 
Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more flexible, or plastic, stem-cell-like state in the lymph nodes, according to a new preclinical study from Weill Cornell Medicine investigators.
 
   CRISPR for Christmas? The Year’s Biggest Gene Editing Breakthroughs, UnwrappedCRISPR for Christmas? The Year’s Biggest Gene Editing Breakthroughs, Unwrapped
 
In 2025, CRISPR advanced gene editing with safe, effective therapies and AI tools, marking a shift towards real-world applications in medicine and agriculture.
 
   Study Challenges Long-Held Assumptions About Mendelian Retinal DisordersStudy Challenges Long-Held Assumptions About Mendelian Retinal Disorders
 
A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.
 
 Restoring brain energy balance reverses Alzheimer’s disease in mouse models
 
For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.
 
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