Low-dose megestrol strengthens hormone therapy in ER-positive breast cancer

	Oncology
	The latest oncology news from News Medical

	Low-dose megestrol strengthens hormone therapy in ER-positive breast cancer Low-dose megestrol enhances hormone therapy for ER-positive breast cancer, reducing tumor proliferation and improving treatment adherence in the PIONEER trial.

	Recent advances in CAR-NK cell therapy could revolutionize cancer treatment Cell-based immunotherapies have transformed cancer treatment, yet their widespread use remains constrained by safety risks, manufacturing complexity, and limited effectiveness against solid tumors.

	Durvalumab extends survival in small cell lung cancer but raises cost concerns A new study suggests that the immune checkpoint inhibitor, durvalumab, may offer new treatment options for patients living with small cell lung cancer (SCLC).

	Cornell-developed nanoparticles improve cancer immunotherapy effectiveness A class of ultrasmall fluorescent core-shell silica nanoparticles developed at Cornell is showing an unexpected ability to rally the immune system against melanoma and dramatically improve the effectiveness of cancer immunotherapy, according to a new study led by Weill Cornell Medicine and Cornell Engineering researchers.

			New breakthrough could modernize treatment for glioblastoma Researchers at the UNC School of Medicine and the UNC Eshelman School of Pharmacy have made a breakthrough that could modernize treatment for glioblastoma, a fast-growing and deadly form of brain cancer.

			Pitavastatin shows pomise in overcoming chemotherapy resistance in triple-negative breast cancer Triple-negative breast cancer (TNBC) is among the most aggressive types of breast cancer, lacking estrogen, progesterone, and HER2 receptors and thus relying primarily on cytotoxic chemotherapy.

			Advanced AI provides accurate guidance for prostate cancer patients Mayo Clinic researchers have developed and evaluated MedEduChat, an electronic health record (EHR) that works with a large language model to provide accurate, patient-specific prostate cancer education.

			Digital twin technology guides personalized treatment for brain cancer patients A new machine-learning-based approach to mapping real-time tumor metabolism in brain cancer patients, developed at the University of Michigan, could help doctors discover which treatment strategies are most likely to be effective against individual cases of glioma.

	Breakthrough treatment for advanced prostate cancer could eliminate severe side effects Researchers at Case Western Reserve University have developed a treatment for advanced prostate cancer that could eliminate a side effect so debilitating that patients often refuse the life-saving therapy.

	Individualized drug combinations improve cancer treatment outcomes Researchers at University of California San Diego School of Medicine have led the first clinical trial in the world to show that cancer drug treatments can be safely and effectively personalized based on the unique DNA of a patient's tumor.

	AI-designed molecular sensors could enable early detection of cancer Detecting cancer in the earliest stages could dramatically reduce cancer deaths because cancers are usually easier to treat when caught early.

	Sugarcane protein mouthwash helps protect oral health during head and neck cancer treatment An artificial saliva in the form of a mouthwash, produced with the CANECPI-5 protein extracted from sugarcane and modified in a laboratory, can aid in treating teeth in patients with head and neck cancer. In these cases, radiotherapy very close to the mouth can destroy salivary glands and compromise saliva production, which is essential for controlling bacteria and disease.

	UVA researcher wins $700,000 for promising ovarian cancer research Promising ovarian cancer research by Melanie Rutkowski, PhD, at the University of Virginia Comprehensive Cancer Center has won $700,000 in support from the Victoria's Secret Global Fund for Women's Cancers in partnership with Pelotonia and AACR, the American Association for Cancer Research.

	Brazilian study shows liquid biopsies can expedite lung cancer care In Brazil, the early detection of genetic alterations in lung cancer through liquid biopsies could be a valuable tool for expediting diagnoses and guiding patient treatment.

	Researchers develop enhanced antibodies to unleash the immune system against cancer Researchers at the University of Southampton have developed a promising new way to bolster the body's immune system response to cancer.

	Personalized cancer therapy significantly enhances treatment success Researchers at University of California San Diego School of Medicine have led the first clinical trial in the world to show that cancer drug treatments can be safely and effectively personalized based on the unique DNA of a patient's tumor.

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