CT-based quantification of tumor fibrosis guides chemotherapy in pancreatic cancer
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 ECG-based AI model doubles early liver disease diagnosesECG-based AI model doubles early liver disease diagnoses
 
As rates of obesity, high blood pressure, type 2 diabetes and sleep apnea increase, cases of advanced chronic liver disease and resulting liver scarring or cirrhosis also are rising. Patients often are diagnosed based on symptoms, such as gastrointestinal bleeding, fluid retention or jaundice, which happen when liver disease has progressed to a late stage.
 
 
 CT-based quantification of tumor fibrosis guides chemotherapy in pancreatic cancerCT-based quantification of tumor fibrosis guides chemotherapy in pancreatic cancer
 
On October 3, 2025, a multicenter team from Shenzhen University, Xiangya Hospital of Central South University, Zhujiang Hospital of Southern Medical University, Wuxi People's Hospital Affiliated to Nanjing Medical University, among others jointly reported a novel noninvasive method for quantifying tumor fibrosis based on preoperative enhanced CT.
 
   Fatty diets reprogram hepatocytes and increase liver cancer riskFatty diets reprogram hepatocytes and increase liver cancer risk
 
One of the biggest risk factors for developing liver cancer is a high-fat diet. A new study from MIT reveals how a fatty diet rewires liver cells and makes them more prone to becoming cancerous.
 
   Forever chemicals linked to higher liver disease risk in adolescentsForever chemicals linked to higher liver disease risk in adolescents
 
A new study co-led by the Southern California Superfund Research and Training Program for PFAS Assessment, Remediation and Prevention (ShARP) Center and the University of Hawai'i has linked certain common "forever chemicals" to a higher risk of liver disease in adolescents.
 
   Using contrast-enhanced ultrasound to distinguish hepatic PEComa from HCC without high-risk factorsUsing contrast-enhanced ultrasound to distinguish hepatic PEComa from HCC without high-risk factors
 
Announcing a new article publication for BIO Integration journal. Hepatic perivascular epithelioid cell tumor (PEComa) is a rare tumor with malignant potential that is frequently misdiagnosed as hepatocellular carcinoma (HCC), despite requiring distinct treatment approaches.
 
 Discovery of fat-regulating enzyme points to a new obesity therapy
 
Discovery of fat-regulating enzyme points to a new obesity therapyObesity is a global epidemic and a major cause of morbidity and mortality because it increases the risk for comorbidities, including heart disease and fatty liver disease (MASLD).
 
 
 Repurposed drug combination shows strong promise against liver fibrosis
 
The study shows that this drug pair works far better together than either agent alone, offering a realistic and potentially fast path toward a new antifibrotic therapy.
 
 
 New tool can predict recurrence risk in patients with pancreatic neuroendocrine tumors
 
Cedars-Sinai investigators, leading a multi-institutional team, have developed and validated a tool to predict which patients with pancreatic neuroendocrine tumors (PanNETs) need closer monitoring because their cancer is more likely to recur.
 
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